None of the charm of the Mother-32, DFAM, or Submarmonicon, no. It might appeal to new people, I could see that.
Oh, it'll definitely appeal to old people, too, especially those of us who look back on this form factor with fondness.
Although I sold my Mother-32 pretty quickly, I have to say that its voicing was very nice. My Little Phatty seemed sort of constrained to the low- and mid-range, but the M32 really sparkled in the upper registers. If the voicing on the Grandmother is similar to that of the Mother-32, then it will be a nicer all-around instrument than the Little Phatty (with the unfortunate exception of keyboard length).
If I hadn't moved to a keyboard-less modular synth, the Grandmother would be on my short list. And I'm definitely not a new person.
It will be interesting to see how its oscillators track volt-per-octave. The post-Briar Moog instruments--the Voyager, Little Phatty, Minitaur--were not factory-calibrated, nor did they have a factory-installed calibration trimpot. Mother-32 was better, but still not well-calibrated like a good eurorack oscillator. It's time for Moog to pay some attention to this.