Hi,
There aren't any significant hardware changes from serial number 1 to the most recent SN. Pots and encoders with some lateral movement are not tied to any serial range. Generally speaking, the potentiometers and encoders used are incredibly robust and we rarely see problems with them in the field. Some movement is normal as the pots/encoders aren't bolted to the metalwork, the lateral tolerance is also in the parts specification. If any parameters do stop working or start skipping values, reach out to support@sequential.com and we can help you out.
I'll also copy a reply from a recent thread below on sound differences between serial ranges...
Good luck! If I were buying a used unit, I would ask the seller if calibration passes (Preset + 0).
Quote from: RMVS on August 13, 2024, 07:23:28 AM
Someone over on reddit is claiming that their 2017 and 2023 Pro-6s sounds "completely" different, i.e., there is more bass and better HPF resonance on the newer version. They suggest this is due to chip changes during production.. This honestly sounds bogus to me since it hasn't been documented anywhere, but it's a strong claim.. anyone noticed any differences/have any further evidence of this?
Changes in production happen fairly often, especially with something like the Prophet-6 which has been manufactured for over 8 years. Parts can get EOL'd or might get hard to get, new versions become available, parts get priced out, and so on. With that said, there have been no changes to the core voice of the Prophet-6/OB-6. Slight variation is expected unit to unit given the density of components in the signal path, and on an older unit things like age, component tolerance, or use might have a slight impact as well. They're still built in SF, from serial 1 and on.