As mentioned above, anyone experiencing this issue should contact support@sequential.com. Getting the details logged on our end is crucial and will help us find a fix.
Good troubleshooting will also help here. Does it happen with Local Control OFF? With all MIDI applications closed, does it occur with only DIN out connected? Does it occur over USB? If only via DIN, does it occur with a different MIDI interface? Does it occur on another computer, or perhaps another computer running a different operating system?