After extensive testing of clock-accuracy when slaved to an external clock over MIDI DIN or USB, it appears that the sequencer and arpeggiator is consistently 18-20 ms early.
Most hardware instruments are usually a little late (8 - 15 ms is common), but that is fine as they all end up in the same ballpark anyway and the end result sounds fine.
But since the Take 5 seq/arp is early by such a large amount, it is VERY noticeable (Take 5 is 20 ms early, other instruments are approx 10 ms late, difference is 30 ms !!).
I can compensate the differences in MIDI timing in my DAW, but when playing live on a "dawless" rig using MIDI DIN, this is not an option.
The timing issue is present regardless if I use MIDI DIN or USB MIDI. I didn't test this before the .22 beta firmware, so I am not sure if this is a new issue or old.