I don't have a Take 5. I have a P5 and a P6, though. I've been a Prologue fan from the start and one thing I love about it is that it's indeed quite a complimentary synth in contrast to others. It's got a thinner sound than Sequential synths, but it's got a really nice range from pretty/beautiful to freaky/weird. It balances with/against my Sequential gear.
I recently sold my Juno 6 after having picked up the Roland System 8, which, has to be said, can utterly nail the Juno sound. The Juno, while also being pals with my Sequential gear, often felt like it was saying, "But me! I'm here... you don't need those other synths!" The Prologue isn't showy, even when it's generating the loveliest of tones.