I use Cubase 11 on Windows 10 & I can't get this crap software to connect via USB. Instructions are straightforward enough & I've checked the setting dozens of times...
Anybody have some luck?
Late answer, but anyway... I first had problems connecting the the Pro-2 using Windows-10. When I contacted the Soundtower support about it showed out that I had not downloaded the latest version of the editor. The download webpage was a bit confusing and I had downloaded an earlier version that didn't work well. With the latest version I didn't have any problems connecting to the Pro-2.
You say you're using Cubase, so are you using the plugin version of the editor? I haven't tried that, only the standalone version of the editor. But my guess is that it's basically the same software under the hood, so maybe it is the exact same problem.