After several months of use, my OB6 will still need the occasional call to the auto-tune routine from time to time, because it will drift slightly out of tune. Even after clearing the temperature table and painstakingly refilling it with new values over several weeks of use.
Much like the Prophet 5, which required the occasional "Tune" also, but much less severe than on a Memorymoog. ;-)
It's the nature of an analog beast I guess.
I don't believe in the claims made by several DSI service reps (contacted over the months on the issue) about the synth being in tune from power-on to hours on end. I've yet to experience that reliably on my OB6 (module version). It's not preventing me from enjoying the synth though, as the immediate fix is easy enough (pressing "Manual" and "0" buttons) and doesn't take much time. But then again I don't do live shows where a synth that slowly goes sharp by half a semitone would be a little embarrassing...