My old e5kultra was both a performance sampler and a programmer's sampler. Could be used as a dynamic semi-rompuler or a complete sample workstation. The only thing I found a computer made easier was naming, but with a ps2 keyboard that was not even an issue.
Now, I know that the E4Kultra range is overkill for what y'all are throwing around, but it's a good example of high quality sampling within a hardware box. The filters are incredible on those things also.
Nor does it imply that there aren't, for some sampling workflows, hardware approaches to editing that are intuitive, e.g., the Akai S612 loop-start / -end sliders.
Oh they were fun, especially when flipping the slider sides into reverse play. So noisy, so dirty, so easy to use without a manual! Too bad the disc format was pretty much abandon by the end of the 80's.
I really think that when using screens like that on a micoSampler or ES2, sliders for start/end points would give that immediate control that one wants for live sampling. Even with samplers made for in-the-box editing, for all the joy a large screen that can display waveforms brings, trying to edit on-the-fly using my MV8000 is not really feasible. The e5k was more usable in that way when left operating in sample edit mode but you couldn't quickly create a complete multi-assigned performance patch and was more like working with an Akai S612 (which I was quite happy with doing).
Oh yeah, I bought a Microgranny recently which has some very unique concepts for a hardware sampler (or granular synth as it's being sold as). One function is to spread the "grains" of the sample across the keyboard, which essentially creates a multi-assign sampled instrument instantly, avoiding frequency stretch/compression that limits the usable keyboard range when assigning one sample to the entire 10 octaves. The MG isn't perfect by any stretch of the imagination; it's monophonic, the onboard mic is activated by a clicking button which slaps a thud into the attack of every sample it captures, it uses 1/8" jacks for everything bar MIDI, but it's an interesting take on the live hardware sampler which can be successfully run in a improvising situation. Using such an engine as the basis for a more complete sampling instrument with analogue elements also in the flow would be wonderful.